OBJECTIVE: To probe into the implementation effect of the first batch of pilot project of nationalorganized centralized drug procurement and application（ hereinafter referred to as "national centralized procurement"）in the first contract year in a certain grade Ⅲ level A general hospital in Chongqing（ hereinafter referred to as "this hospital"）

and to sum up the experience

so as to provide references for the bid-continuing of the first batch of national centralized procurement and the execution of the second and the third batches

and to explore the role and value of hospital pharmacists in the pilot process. METHODS: Data of drug application of the 2019 contract period and the same period in 2018 for a total of 24 months in this hospital were retrieved and analyze in combination with national policies and hospital implementation plans. RESULTS: In the 2019 contract period

this hospital had overfulfilled the task volume and proportion of bid-winning drugs issued by the Medical Insurance Bureau. Compared with the same period in 2018

after the implementation of national centralized procurement

the total usage amount of bid-winning drugs in this hospital had increased from 13. 335 9 million tablets（ pieces） to 14. 005 2 million tablets（ pieces）

with an increase of 669 300 tablets（ pieces） and an increasing amplitude of 5. 02%; the total consumption sum had decreased from 102. 332 million yuan to 63. 835 7 million yuan

with a decrease of 38. 496 3 million yuan and decreasing amplitude of 37. 62%.CONCLUSIONS: The implementation of national centralized procurement policy can effectively reduce drug expenditure

relieve economic burden of patients and promote rational application of generic drugs. Hospital pharmacists can play an active role in drug catalog optimizing

policy training

data monitoring and rational medication controlling.