OBJECTIVE: To probe into the effects of enteral nutrition solution at different temperature on gastrointestinal complications in patients undergoing radical gastrectomy. METHODS: Totally 180 patients undergoing radical gastrectomy admitted into Jiangsu Provincial Hospital of Traditional Chinese Medicine from 2018 to 2019 were extracted to be divided into the the low temperature group

body temperature group and high temperature group via the random number table

with 60 cases in each group. The low temperature group was treated with enteral nutrient solution below body temperature（ from 33. 0 ℃ to 35. 9 ℃）

the body temperature group was treated with enteral nutrient solution close to body temperature（ from 36. 0 ℃ to 38. 0 ℃）

and the high temperature group received enteral nutrient solution above body temperature（ from 38. 1 ℃ to 42. 0 ℃） . Differences of gastrointestinal hormones[gastrin（ GAS）

motilin（ MTL） and cholecystokinin（ CCK） ]

intestinal mucosal function [diamine oxidase（ DAO）

D-lactic acid（ D-LA） and lactolose/mannitol ratio（ L/M） ] and the incidence of gastrointestinal complications of three groups were compared. RESULTS: After 3 and 7 d of treatment

the levels of GAS

MTL and CCK in the low temperature group

body temperature group and high temperature group were significantly higher than those before treatment

and the levels of GAS

MTL and CCK in the body temperature group were significantly higher than those in the low temperature group and high temperature group

with statistically significant difference（ P<0. 05）.After 3 and 7 d of treatment

DAO

D-LA and L/M in the low temperature group

body temperature group and high temperature group were significantly lower than those before treatment

while DAO

D-LA and L/M in the body temperature group were significantly lower than those in the low temperature group and high temperature group

with statistically significant difference（ P< 0. 05）. The incidence of gastrointestinal complications in the body temperature group was 10. 00%（ 6/60）

significantly lower than 33. 33%（ 20/60） in the low temperature group and 26. 67%（ 16/60） in the high temperature group

the difference was statistically significant（ P < 0. 05）. CONCLUSIONS:Intestinal nutrient solution close to body temperature（ from 36. 0 ℃ to 38. 0 ℃） can effectively improve the gastrointestinal hormone and intestinal mucosal function in patients undergoing radical gastrectomy

which is beneficial to reduce gastrointestinal complications.