Epidemiological Characteristics of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections Based on Bayesian Network and Decision Tree
LI Li, QIN Huilian, GAN Jianzhong, et al. Epidemiological Characteristics of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections Based on Bayesian Network and Decision Tree[J]. 2021,21(1):101-104.
LI Li, QIN Huilian, GAN Jianzhong, et al. Epidemiological Characteristics of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections Based on Bayesian Network and Decision Tree[J]. 2021,21(1):101-104. DOI: 10.14009/j.issn.1672-2124.2021.01.025.
基于贝叶斯网络与决策树的中药注射剂致药品不良反应的流行病学特点研究
摘要
目的:探讨广西壮族自治区梧州市(以下简称"梧州地区")中药注射剂致药品不良反应(adverse drug reaction
OBJECTIVE: To probe into the epidemiological characteristics of adverse drug reactions( ADR)induced by traditional Chinese medicine injections in Wuzhou
Guangxi Zhuang Autonomous Region( Hereinafter referred to as "Wuzhou"). METHODS: ADR reports induced by traditional Chinese medicine injections in Wuzhou from 2011 to 2019 were collected. Microsoft ACCESS software was used to establish the database
and SPSS Modeler14. 1 data mining platform was used to carry out data mining research based on CART
CHAID decision tree algorithm and Bayesian network methods. RESULTS: A total of 1 370 detailed cases of ADR induced by traditional Chinese medicine injections were collected
of which 1 239 cases were general( 90. 44%) and 131 cases were severe( 9. 56%). The results of Bayesian network analysis showed that the clinical manifestations of ADR induced by traditional Chinese medicine injection were related to the age of patients. In the age group of > 60 years old
the proportion of skin damage gradually decreased
and the proportion of other system damage gradually increased. The results of cart algorithm showed that the main clinical manifestation of ADR was skin damage
and skin damage was the main manifestation of ADR in all age groups. The results of decision tree CHAID algorithm show that the main clinical manifestation of ADR was skin damage
the general ADR was mainly skin damage
and the serious ADR were mainly systemic damage and respiratory damage.. CONCLUSIONS: The epidemiological characteristics of ADR induced by traditional Chinese medicine injections in Wuzhou may be related to the age of patients
occurrence time of ADR and types of ADR
which need to be analyzed and verified by data analysis of a larger sample size.
关键词
中药注射剂数据挖掘药品不良反应决策树贝叶斯网络
Keywords
Traditional Chinese medicine injectionsData miningAdverse drug reactionsDecision treeBayesian network