OBJECTIVE: To evaluate the intervention effects of service model based on medication therapy management（ MTM） on elderly patients with hypertension in community. METHODS: A randomized

controlled study was designed to screen 90 elderly patients with hypertension from the contracted community from Dec. 2017 to Jun.2019

all patients were divided into the intervention group and the control group

with 45 cases in each group. The intervention group received MTM-related services

and the control group was given routine medication instructions.Changes in blood pressure control level

medication compliance

medication deviation

and patient satisfaction were evaluated after 6 months. RESULTS: During the follow-up period

1 case in the control group was lost to follow-up（ 1 case died）

a total of 45 patients in the intervention group and 44 cases in the control group were included in the study. Under the premise that there was no significant difference in initial blood pressure between the intervention group and the control group（ P > 0. 05）

the systolic and diastolic blood pressure of the intervention group after MTM was significantly lower than before intervention

and the difference was statistically significant（ tSBP=-3. 628

tDBP=-3. 302; P < 0. 001）; the blood pressure level of the control group was not significantly controlled after 6 months

and the difference was not statistically significant（ P > 0. 05）. The medication compliance of the intervention group was significantly higher than that of the control group

and the difference was statistically significant（ P < 0. 05）. The incidence of medication deviation in the intervention group such as usage and dosage

irrational drug combination

repeated medication

poor drug efficacy

and adverse drug reactions was significantly lower than those in the control group

and the differences were statistically significant（ P < 0. 05）. The satisfaction of patients in the intervention group to pharmaceutical services was significantly higher than that of the control group

the difference was statistically significant（ P < 0. 05）. CONCLUSIONS: The implementation of MTM service can improve the blood pressure control level of elderly hypertensive patients in the community

and improve the safety

effectiveness and patient satisfaction.