OBJECTIVE: To establish the characteristic chromatogram of ultra performance liquid chromatography（ UPLC） of Albizia flower

and to rapidly identify its main chemical components based on ultra performance liquid chromatography-tandem quadrupole-time of flight mass spectrometry（ UPLC-Q/TOF-MS）. METHODS: CORTECS UPLC T3 chromatographic column（ Waters

2. 1 mm × 100 mm

1. 6 μm）

using 0. 1% phosphoric acid solutionacetonitrile as mobile phase

with the column temperature was 35 ℃

flow rate was 0. 30 ml/min

gradient elution

detection wavelength was 220 nm

scanned in positive and negative ion mode. RESULTS: Totally 5 common peaks were marked in the characteristic chromatogram of Albizia flower

and the relative retention time RSD of each common peak was < 2% after the identification of mass spectrometry; totally 17 compounds were identified by qualitative analysis

including 2 free amino acids

1 organic acids

12 flavonoids and glycosides

and 1 triterpene saponins.CONCLUSIONS: This method is simple

fast

efficient and accurate

which provides scientific basis for the quality control of later medicinal materials and further clarification of pharmacodynamic material basis.