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1. 上海中医药大学附属市中医医院心内科
2. 同济大学附属上海市第十人民医院中医科
纸质出版日期:2021,
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[1]胡晓贞,韩天雄,周苗,翁嘉灏,王祎晟,赖志昆,冯其茂.温阳活血方联合常规心脏康复改善冠心病经皮冠状动脉介入术后患者生活质量的临床研究[J].中国医院用药评价与分析,2021,21(01):11-14+18.
HU Xiaozhen, HAN Tianxiong, ZHOU Miao, et al. Clinical Study of Wenyang Huoxue Decoction Combined with Routine Cardiac Rehabilitation on Improvement of Life Quality of Patients with Coronary Heart Disease After Intervention[J]. 2021,21(1):11-14.
[1]胡晓贞,韩天雄,周苗,翁嘉灏,王祎晟,赖志昆,冯其茂.温阳活血方联合常规心脏康复改善冠心病经皮冠状动脉介入术后患者生活质量的临床研究[J].中国医院用药评价与分析,2021,21(01):11-14+18. DOI: 10.14009/j.issn.1672-2124.2021.01.003.
HU Xiaozhen, HAN Tianxiong, ZHOU Miao, et al. Clinical Study of Wenyang Huoxue Decoction Combined with Routine Cardiac Rehabilitation on Improvement of Life Quality of Patients with Coronary Heart Disease After Intervention[J]. 2021,21(1):11-14. DOI: 10.14009/j.issn.1672-2124.2021.01.003.
目的:探讨温阳活血方联合常规心脏康复对冠心病经皮冠状动脉介入术后患者生活质量的改善效果
为中西医结合心脏康复提供临床新证据和新思路。方法:选取2017年6月至2019年11月上海中医药大学附属市中医医院、同济大学附属上海市第十人民医院行经皮冠状动脉介入术成功4周后的患者60例
按随机、对照原则分为治疗组30例和对照组30例。两组患者均采用常规西药及心脏康复治疗
治疗组患者加用温阳活血方早晚分服
12周为1个疗程。观察两组患者治疗前后中医证候积分、西雅图心绞痛量表(Seattle angina questionnaire
SAQ)评分及健康调查简表(the medical outcomes study item short from health survey
SF-36)评分。结果:两组患者治疗后的中医证候积分较治疗前明显改善
同时治疗组患者的改善程度优于对照组
差异均有统计学意义(P <0.05)。治疗组患者的总有效率为90.0%(27/30)
较对照组的66.7%(20/30)明显改善
差异有统计学意义(P <0.05)。治疗后
治疗组患者的SAQ评分(包括躯体活动受限程度、心绞痛稳定程度、心绞痛发作频率、治疗满意度及疾病认知)明显优于对照组
差异均有统计学意义(P <0.05)。治疗组患者治疗后的SF-36各项评分均较治疗前明显升高;对照组患者治疗后的生理机能、生理职能、躯体疼痛和精力等4个维度评分明显高于治疗前;治疗组患者治疗后的躯体疼痛、精神健康、社会功能、情感职能和总体健康等5个维度评分均较对照组明显升高
上述差异均有统计学意义(P <0.05)。结论:温阳活血方联合常规心脏康复可以改善患者的中医证候积分
改善心绞痛症状
提高生活质量
疗效确切。
OBJECTIVE: To probe into the clinical study of Wenyang Huoxue decoction combined with routine cardiac rehabilitation on improvement of life quality of patients with coronary heart disease after intervention
so as to provide new clinical evidence and new ideas for the cardiac rehabilitation with the combination of traditional Chinese medicine and Western medicine. METHODS: From Jun. 2017 to Nov. 2019
60 patients undergoing successful percutaneous coronary intervention in Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine and Tenth People ’s Hospital of Tongji University were extracted to be divided into the treatment group and the control group according to the principle of randomization and comparison
with30 cases in each group. Patients in both groups were treated with routine western medicine and cardiac rehabilitation.The treatment group was given Wenyang Huoxue decoction in the morning and evening
for 12 weeks as a course of treatment. Traditional Chinese medicine syndrome scores
Seattle angina questionnaire( SAQ) score and the Medical Outcomes Study item short from health survey( SF-36) of two groups were observed before and after treatment.RESULTS: After treatment
the traditional Chinese medicine syndrome score in both groups was improved significantly compared with that before treatment
and the improvement in the treatment group was better than that in the control group
with statistically significant differences( P < 0. 05). The total effective rate in the treatment group was 90. 0%( 27/30)
significantly higher than 66. 7%( 20/30) in the control group
the difference was statistically significant( P < 0. 05). After treatment
the SAQ scores( including physical activity limitation
angina stability
angina pectoris frequency
treatment satisfaction and disease cognition) of the treatment group were significantly better than those of the control group
and the differences were statistically significant( P < 0. 05); the SF-36 scores in the treatment group after treatment were significantly higher than those before treatment; the scores of physiology
physiological function
physical pain and energy in the control group were significantly higher than those before treatment; after treatment
the scores of physical pain
mental health
social function
emotional function and overall health in the treatment group were significantly higher than those in the control group
and the differences were statistically significant( P < 0. 05).CONCLUSIONS: Wenyang Huoxue decoction combined with routine cardiac rehabilitation can improve the traditional Chinese medicine syndrome score
angina pectoris and life quality.
温阳活血方心脏康复结合治疗经皮冠脉介入术后生活质量
Wenyang Huoxue decoctionCardiac rehabilitationCombination therapyAfter coronary interventionLife quality
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