OBJECTIVE:To probe into the effect of Quyou decotion combined with photodynamic therapy on the degree of skin lesion

quality of life and recurrence in patients with intractable plantar warts of damp-heat and blood stasis type.METHODS:Totally 100 patients with intractable plantar warts of damp-heat and blood stasis type admitted into Hebei Petro China Central Hospital and Langfang People’s Hospital from Mar.2018 to Jun.2019 were selected and divided into control group and observation group via random number table

with 50 cases in each group.The control group was given photodynamic therapy combined with tretinoin cream for external use;while the observation group was given photodynamic’therapy combined Quyou decoction for soaking.The clinical efficacy

improvements of skin lesion

quality of life

T cell subset and recurrence of both groups were observed.RESULTS:The total effective rate of observation group was 92.00%（46/50）

which was significantly higher than that of the control group（74.00%

37/50）

with statistically significant difference（P

<

0.05）;after treatment

the various scores of skin lesion and the total scores of QOL indicator of the two groups were significantly lower than those of before treatment

and those of the observation group were significantly lower than the control group

with statistically significant differences（P

<

0.05）.After treatment

the CD3

+

CD4

+

and CD4

+

/CD8

+

levels of both groups were significantly higher than those of before treatment

and those of the observation group were significantly higher than the control group

with statistically significant differences（P

<

0.05）;while there was no statistical significance in difference in CD8

+

levels between two groups before and after treatment（P

>

0.05）.The recurrence rate of observation group was4.00%（2/50）

which was significantly lower than that of the control group（18.00%

9/50）

with statistically significant difference（P

<

0.05）.CONCLUSIONS:For patients with intractable plantar warts of damp-heat and blood stasis type

Quyou decoction combined with photodynamic therapy is more effective than photodynamic therapy combined with tretinoin cream

which can effectively promote the regression of skin lesions

significantly improve their quality of life and cellular immune function

and significantly reduce the risk of recurrence.