OBJECTIVE: To probe into the clinical characteristics of patients with COVID-19

and to summarize the whole process of integrated traditional Chinese and Western medicine treatment and the development and outcome of the patients’ condition. METHODS: The information management system of Donghua Hospital and Meikang clinical pharmacy management system were used

20 patients diagnosed with common COVID-19 in Wuhan Third Hospital from Jan. 25th to Mar. 5th

2020 were selected as the research objects for retrospective analysis. Twenty patients received antiviral treatment from the time of diagnosis

including continuous oral administration of oseltamivir for 5 d

continuous oral administration of abidol for 5 to 10 d

and continuous oral administration of Lianhua Qingwen granules for 5 to 10 d.In addition

all patients received moxifloxacin treatment and other necessary supportive care （oxygen inhalation and nutritional support were given according to patients’ condition） for 3 to 6 d. RESULTS: After treatment of integrated traditional Chinese and Western medicine

all clinical symptoms related to COVID-19 of 20 patients disappeared

white blood cell count

neutrophil percentage and lymphocyte percentage all returned to the normal levels

and chest CT examination results showed that the infection lesions were obviously absorbed. All patients were tested three times for viral nucleic acids

which were negative and discharged from the hospital. CONCLUSIONS: The results of this study provide clues for the treatment of COVID-19

and the efficacy

safety and rationality of oseltamivir

abidor

Lianhua Qingwen granules combined with moxixacin are supposed to be further verified in future studies.