Model-based meta-analysis（MBMA） is a type of quantitative pharmacological method.Based on the previous clinical research data

pharmacodynamic model and statistical model are established

and covariates are introduced to predict the drug efficacy.MBMA can provide an effective method for the selection of treatment drugs for type 2 diabetes mellitus

establish a model to compare and analyze various hypoglycemic drugs in the aspects of blood glucose control

weight change and hypoglycemia risk

simulate and predict different dosage and treatment interval

so as to improve the basis for specialists to carry out individualized treatment in different patients.