中药外用制剂治疗白癜风的用药规律挖掘研究

车智慧; 袁宁泽; 张婷; 刘肖; 袁海龙

doi:10.14009/j.issn.1672-2124.2020.08.021

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中药外用制剂治疗白癜风的用药规律挖掘研究

用药分析 | 更新时间：2022-10-08

- 中药外用制剂治疗白癜风的用药规律挖掘研究
- Application Rules of External Preparations of Traditional Chinese Medicine in the Treatment of Vitiligo
- 中国医院用药评价与分析 2020年20卷第8期页码：976-978
- 作者机构：
  
  1. 安徽医科大学空军临床学院
  2. 空军特色医学中心药学部
  3. 北京科技大学计算机与通信工程学院
- 作者简介：
- 基金信息：
  
  北京市自然科学基金（No.Y171006）;军队后勤重点项目（No.BKJ15J005）
- DOI：10.14009/j.issn.1672-2124.2020.08.021
  中图分类号： R275.9
- 纸质出版日期：2020，
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[1]车智慧,袁宁泽,张婷,刘肖,袁海龙.中药外用制剂治疗白癜风的用药规律挖掘研究[J].中国医院用药评价与分析,2020,20(08):976-978.

CHE Zhihui, YUAN Ningze, ZHANG Ting, et al. Application Rules of External Preparations of Traditional Chinese Medicine in the Treatment of Vitiligo[J]. 2020,20(8):976-978.
[1]车智慧,袁宁泽,张婷,刘肖,袁海龙.中药外用制剂治疗白癜风的用药规律挖掘研究[J].中国医院用药评价与分析,2020,20(08):976-978. DOI： 10.14009/j.issn.1672-2124.2020.08.021.

CHE Zhihui, YUAN Ningze, ZHANG Ting, et al. Application Rules of External Preparations of Traditional Chinese Medicine in the Treatment of Vitiligo[J]. 2020,20(8):976-978. DOI： 10.14009/j.issn.1672-2124.2020.08.021.

摘要

目的:基于数据挖掘方法

探讨中药外用制剂治疗白癜风的用药规律。方法:对近5年来应用中药外用制剂治疗白癜风的相关文献进行收集整理

建立数据库

并对中药种类及单味中药进行频次分析

对药物之间进行系统聚类分析及关联规则分析。结果:共收集到符合要求的处方61首

包含中药95味

总使用频次为388次。频次最高的药物类别为补益药

共计127次

含21味中药

其次依次为活血祛瘀药、解表药等。频次最高的单味中药为补骨脂

共计46次。聚类分析结果为3类。使用频次高药物的关联规则分析共得到13种关联较强的药物组合

补骨脂在12种组合中均有出现。结论:中药外用制剂治疗白癜风的常用药物类别为补益药、活血祛瘀药和解表药

其中补骨脂为最常用的单味中药。

Abstract

OBJECTIVE:To explore the application rules of external preparations of traditional Chinese medicine in the treatment of vitiligo based on data mining method.METHODS:Literature about treatment for vitiligo based on external preparations of traditional Chinese medicine in recent five years were retrieved to establish the database.Frequency analysis

system cluster analysis and association rule analysis were performed on categories of traditional Chinese medicine and single traditional Chinese medicine.RESULTS:A total of 61 prescriptions were collected

including 95 kinds of traditional Chinese medicine

with a total frequency of 388.Deficiency-nourishing medicine had the highest frequency of 127 times

including 21 kinds of traditional Chinese medicine

followed by promoting blood circulation and reducing stasis medicine and exterior-effusing medicine.The single traditional Chinese medicine with the highest frequency of 46 times was psoralea fructus.Cluster analysis resulted in 3 categories.The association rule analysis of high-frequency drug use yielded a total of 13 combinations of drugs with strong association

and fructus psoraleae was present in 12 combinations.CONCLUSIONS:The commonly used external preparations of traditional Chinese medicine in the treatment of vitiligo were deficiency-nourishing medicine

promoting blood circulation and reducing stasis medicine and exterior-effusing medicine

and fructus psoraleae is the most commonly used single traditional Chinese medicine.

关键词

白癜风中药外用制剂数据挖掘用药规律

Keywords

VitiligoExternal preparations of traditional Chinese medicineData miningMedication rules

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