OBJECTIVE: To probe into the standardized antibiotics management mode established by clinical pharmacists in urinary surgery department from Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital（ hereinafter referred to as"our hospital"）

and to summarize the effectiveness.METHODS: According to the foreign antimicrobial stewardship（ AMS） mode and the relevant guidelines and consensus on the application of antibiotics in urinary surgery department

the clinical pharmacists

clinicians and nurses of urinary surgery department and antiinfective clinicians jointly studied and discussed to formulate rational application standard of antibiotics and standardized antibiotics management mode in urinary surgery department.The medical record information of inpatients with application of antibiotics in urinary surgery department before implementation of AMS（ discharged from Jan.to Feb.2018）

during implementation（ discharged from Mar.to Apr.2018） and after implementation（ discharged from May to Jun.2018） were extracted.Outpatient prescriptions of urinary surgery department from Jan.to Jun.2018 were selected.The application of antibiotics in urology surgery department was reviewed and evaluated.RESULTS: The application rate of antibiotics for inpatients in urology surgery department of our hospital before implementation of AMS

during implementation and after implementation were respectively 75.27%（ 210/279）

71.83%（ 204/284） and69.44%（ 234/337）

with no statistical significance（ P > 0.05）.The defined daily dose system were respectively80.41

70.69 and 61.94 DDDs/（ 100 people·d）

the difference was statistically significant（ P < 0.05）.The proportion of inappropriate application of antibiotics were respectively 26.19%（ 55/210）

20.10%（ 41/204） and11.54%（ 27/234）

with statistically significant difference（ P < 0.05）.The proportion of outpatient antimicrobial prescriptions were respectively 15.10%（ 335/2 218）

12.84%（ 330/2 570） and 11.28%（ 324/2 873）

with statistically significant difference（ P < 0.05）.CONCLUSIONS: The involvement of clinical pharmacists of urinary surgery department in the standardized antibiotics management is helpful to promote the rational application of antibiotics.