Extended spectrum β lactamases（ ESBL） producing Enterobacteriaceae are important pathogens causing bloodstream infections.Carbapenem antibioics are one of the effective drugs for the treatment of severe infections caused by the multi-resistant bacteria. Recent studies have found that piperacillin tazobactam is effective against bloodstream infections caused by ESBL producing Enterobacteriaceae L and may be an effective alternative to reduce bacterial resistance to carbapenem antibioics.This thesis mainly summarizes the clinical efficacy of piperacillin tazobactam in the treatment of bloodstream infections caused by ESBL producing Enterobacteriaceae in recent years

and aims to provide reference for clinical medication.