OBJECTIVE: To probe into the role of therapeutic drug monitoring in the rescue of patients with carbamazepine intoxication

and to provide reference for clinical resolution of carbamazepine intoxication. METHODS:Medical records for patients with carbamazepine intoxication were collected. Based on therapeutic drug monitoring results

the diagnosis and treatment process were thoroughly reviewed. RESULTS: Three cases of carbamazepine intoxication were included and analyzed

and the diagnosis was clarified with the help of therapeutic drug monitoring results during the clinical treatment

and the blood concentration of carbamazepine was repeatedly reviewed to determine the clinical efficacy. CONCLUSIONS: Therapeutic drug monitoring can provide basis for clinical diagnosis of carbamazepine intoxication and guide the adjustment of intoxication treatment strategy.