OBJECTIVE: To probe into the application rationality of parenteral nutrition prescriptions in the Seventh Affiliated Hospital of Sun Yat-sen University（ hereinafter referred to as "our hospital"）

so as to provide reference for further optimizing the review rules of pharmacy intravenous admixture service（ PIVAS） and implementing pharmaceutical interventions. METHODS: Through HIS system

a total of 1 944 parenteral nutrition prescriptions from May 2018 to Sept.2019 were extracted. The stability and effectiveness of prescriptions were evaluated

including glucose concentration

amino acid concentration

cation concentration

addition of other therapeutic drugs

ratio of glucose to lipid

ratio of heat to nitrogen

and application of pharmacological nutrients. RESULTS: Of the 1 944 prescriptions

1 063 prescriptions were rational

with the rational rate of 54. 68%. There were 881 irrational prescriptions

including 457 prescriptions（ 51. 87%） with irrational ratio of glucose to lipid

449 prescriptions（ 50. 96%） with irrational ratio of heat to nitrogen

313 prescriptions（ 35. 53%） with irrational amino acid concentration

153 prescriptions（ 17. 37%） with irrational pharmacological nutrients

28 prescriptions（ 3. 18%） with irrational addition of other therapeutic drugs

19 prescriptions（ 2. 16%） with irrational glucose concentration

and 18 prescriptions（ 2. 04%） with irrational cation concentration.CONCLUSIONS: There are some irrational phenomenon of parenteral nutrition prescriptions in the early stage of our hospital. Clinical nutritional pharmacists and PIVAS pharmacists should give full play to their professional skills and conduct real-time review and intervention on parenteral nutrition prescriptions to standardize the clinical application of parenteral nutrition and ensure the safety and effectiveness of patients’ medication.