Effect of Methods of Qi-Tonifying,Yang-Warming,Stasis-Resolving and Diuresis-Promoting on Ventricular Remodeling and Cardiac Function in Patients with Chronic Heart Failure( HeartKidney Yang-Deficiency Type)
JI Feng, REN Yaolong, ZHANG Yuanbo, et al. Effect of Methods of Qi-Tonifying,Yang-Warming,Stasis-Resolving and Diuresis-Promoting on Ventricular Remodeling and Cardiac Function in Patients with Chronic Heart Failure( HeartKidney Yang-Deficiency Type)[J]. 2020,20(5):540-542.
JI Feng, REN Yaolong, ZHANG Yuanbo, et al. Effect of Methods of Qi-Tonifying,Yang-Warming,Stasis-Resolving and Diuresis-Promoting on Ventricular Remodeling and Cardiac Function in Patients with Chronic Heart Failure( HeartKidney Yang-Deficiency Type)[J]. 2020,20(5):540-542. DOI: 10.14009/j.issn.1672-2124.2020.05.008.
OBJECTIVE: To probe into the application value of method of qi-tonifying
yang-warming
stasisresolving and diuresis-promoting in the treatment of chronic heart failure(heart-kidney yang-deficiency type) and its effect on ventricular remodeling and cardiac function. METHODS: Totally 91 patients with chronic heart failure(heartkidney yang-deficiency type) admitted into the Affiliated Hospital of Shaanxi University of TCM from Jun. 2017 to Dec.2018 were enrolled and divided via random number table. The control group(45 cases) was treated with western medicine alone
while the observation group(46 cases) was given traditional Chinese medicine of qi-tonifying
yangwarming
stasis-resolving and diuresis-promoting based on the control group. After 6-month treatment
the lipoproteinrelated phospholipase A2(Lp-PLA2)
angiotensina Ⅱ(Ang Ⅱ)
N-terminal pro B-type natriuretic peptide(NTproBNP)
indices of cardiac ultrasound [left ventricular ejection fraction(LVEF)
left ventricular end systolic diameter(LVESD) and left ventricular end diastolic diameter(LVEDD) ]
6 min walking distance(6 MWD)
scores of living with heart failure questionnaire(LHFQ) and incidences of adverse drug reactions of both groups were observed. RESULTS: After treatment
the Lp-PLA2
Ang Ⅱ and NT-proBNP levels of observation group were significantly lower than those of the control group
with statistically significant differences(P<0. 05). After treatment
the LVEF level of observation group was significantly higher than that of the control group
while the LVESD and LVEDD levels were significantly lower than those of the control group
with statistically significant differences(P <0. 05). After treatment
the LHFQ score of observation group was significantly lower than that of the control group
while the 6 MWD was significantly longer than that of the control group
with statistically significant differences(P<0. 05). The incidences of adverse drug reactions of observation group and control group were respectively 19. 57%(9/46) and 22. 22%(10/45)
the difference was not statistically significant(P>0. 05). CONCLUSIONS: Western medicine combined with traditional Chinese medicine of qi-tonifying
yang-warming
stasis-resolving and diuresispromoting can improve the ventricular remodeling of patients with chronic heart failure(heart-kidney yang-deficiency type)
which can promote the life quality
safe and reliable.
关键词
益气温阳化瘀利水法慢性心力衰竭心肾阳虚型心室重构心功能
Keywords
Method of qi-tonifyingyang-warmingstasis-resolving and diuresis-promotingChronic heart failureHeart-kidney yang-deficiency typeVentricular remodelingCardiac function