临床药师对低体质量慢性血栓栓塞性肺动脉高压患者应用利伐沙班的药学监护及文献复习

李佳乐; 王晓星; 孔旭东; 覃旺军; 赵莉

doi:10.14009/j.issn.1672-2124.2020.04.025

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临床药师对低体质量慢性血栓栓塞性肺动脉高压患者应用利伐沙班的药学监护及文献复习

药学监护 | 更新时间：2022-10-08

- 临床药师对低体质量慢性血栓栓塞性肺动脉高压患者应用利伐沙班的药学监护及文献复习
- Pharmaceutical Care and Literature Review of Rivaroxaban in the Treatment of Low-Weight Patient with Chronic Thromboembolic Pulmonary Hypertension by Clinical Pharmacists
- 中国医院用药评价与分析 2020年20卷第4期页码：480-483
- 作者机构：
  
  1. 广州市妇女儿童医疗中心药学部
  2. 中日友好医院药学部
- 作者简介：
- 基金信息：
  
  北京市自然科学基金项目（No.7192190）;国家重点研发计划项目（No.2016YFC0905600）
- DOI：10.14009/j.issn.1672-2124.2020.04.025
  中图分类号： R544.1
- 纸质出版日期：2020，
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[1]李佳乐,王晓星,孔旭东,覃旺军,赵莉.临床药师对低体质量慢性血栓栓塞性肺动脉高压患者应用利伐沙班的药学监护及文献复习[J].中国医院用药评价与分析,2020,20(04):480-483.

LI Jiale, WANG Xiaoxing, KONG Xudong, et al. Pharmaceutical Care and Literature Review of Rivaroxaban in the Treatment of Low-Weight Patient with Chronic Thromboembolic Pulmonary Hypertension by Clinical Pharmacists[J]. 2020,20(4):480-483.
[1]李佳乐,王晓星,孔旭东,覃旺军,赵莉.临床药师对低体质量慢性血栓栓塞性肺动脉高压患者应用利伐沙班的药学监护及文献复习[J].中国医院用药评价与分析,2020,20(04):480-483. DOI： 10.14009/j.issn.1672-2124.2020.04.025.

LI Jiale, WANG Xiaoxing, KONG Xudong, et al. Pharmaceutical Care and Literature Review of Rivaroxaban in the Treatment of Low-Weight Patient with Chronic Thromboembolic Pulmonary Hypertension by Clinical Pharmacists[J]. 2020,20(4):480-483. DOI： 10.14009/j.issn.1672-2124.2020.04.025.

摘要

目的:探讨低体质量慢性血栓栓塞性肺动脉高压患者服用利伐沙班后凝血异常的原因及剂量选择。方法:临床药师深入临床

对1例低体质量慢性血栓栓塞性肺动脉高压患者实施药学监护。临床药师计算机检索各数据库

结合相关文献

分析患者出现凝血异常的原因

评定患者使用利伐沙班的剂量

提出个体化给药建议。结果与结论:极端体质量患者使用常规剂量的利伐沙班

凝血酶原时间变化有一定的意义

必要时进行血药浓度监测是最佳选择。

Abstract

OBJECTIVE: To probe into the causes and dosage selection of coagulation abnormalities after rivaroxaban administration in low-weight patients with chronic thromboembolic pulmonary hypertension. METHODS:Clinical pharmacists performed pharmaceutical care for the low-weight patients with chronic thromboembolic pulmonary hypertension

searched each database by computer

analyzed the causes of coagulation abnormalities in patients combined with relevant literature

assessed the dose of rivaroxaban used by patients

and proposed individualized drug administration suggestions. RESULTS & CONCLUSIONS: In patients with extreme body weight

the conventional dose of rivaroxaban can be used. The change in prothrombin time is of some significance. And the monitoring of the blood concentration when necessary is the best choice.

关键词

血栓栓塞性肺动脉高压低体质量利伐沙班凝血指标血药浓度

Keywords

Thromboembolic pulmonary hypertensionLow body weightRivaroxabanCoagulation indexBlood concentration

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