Lung transplantation is a widely accepted and effective treatment for end-stage lung disease. In recent decades

with the increase in the number of lung transplants

the surgical indications of patients are in an increasing trend

and the survival rate after transplantation has gradually increased. These successes are not only due to advances in surgical techniques

but effective immunosuppression is also the key success factor. The emergence of various new immunosuppressive drugs improves the immune efficacy

and greatly reduces the occurrence of adverse drug reactions.This paper reviews the latest research advances in the application of immunosuppressant at different stages of lung transplantation

pharmacological mechanisms

efficacy results

and monitoring of therapeutic drugs from the aspects of induced immunotherapy

maintenance immunotherapy and anti-rejection therapy.