ZHANG Lei, LI Qingsong, HUANG Yu. Analysis on Medication Characteristics of Sodium Tanshinone ⅡA Sulfonate Injection in Treatment of Cerebral Infarction Based on Real World[J]. 2020,20(3):340-343.
ZHANG Lei, LI Qingsong, HUANG Yu. Analysis on Medication Characteristics of Sodium Tanshinone ⅡA Sulfonate Injection in Treatment of Cerebral Infarction Based on Real World[J]. 2020,20(3):340-343. DOI: 10.14009/j.issn.1672-2124.2020.03.021.
OBJECTIVE: To investigate the characteristics of clinical application of sodium tanshinone Ⅱ
A
sulfonate injection in treatment of cerebral infarction in the real world
so as to provide references for standardizing clinical medication. METHODS: Based on the hospital information system in Kunshan Hospital of traditional Chinese Medicine
hospitalized cases of 545 patients with cerebral infarction who treated with sodium tanshinone Ⅱ
A
sulfonate injection from 2016 to 2017 were collected and analyzed in terms of patients ’ general information
medication characteristics and drug combination
etc. RESULTS: Of the 545 patients with cerebral infarction who treated with sodium tanshinone Ⅱ
A
sulfonate injection
279 cases were male( 51. 19%)
266 were female( 48. 81%)
with similar proportion; the average age was 66. 84 years old
and most of patients were aged over 45 to 80 years old( 409 cases
75. 05%); all the patients were administered by intravenous drip
with the single dose was mainly 60 mg( 463 cases
84. 95%); the treatment course was mainly 1 to 14 days( 508 cases
93. 21%)
with an average of( 7. 15± 4. 71) d; the drugs used in combination with sodium tanshinone Ⅱ
Rosuvastatin calcium tablets and lipoic acid injection. CONCLUSIONS: The middle-aged and elderly people are the main population for the occurrence of cerebral infarction
the application of sodium tanshinone Ⅱ
A
sulfonate injection is often in combination with anti-platelet aggregation drugs and lipid-regulating drugs
although it conforms to the medication specifications
there are also problems such as over-concentration medications
which should be paid attention.
关键词
丹参酮ⅡA磺酸钠注射液脑梗死用药特征联合用药真实世界研究
Keywords
Sodium tanshinone ⅡA sulfonate injectionCerebral infarctionMedication characteristicsDrug combinationReal world study