OBJECTIVE: To probe into the Efficacy of compound Taizishen granule combined with conventional western medicine in treatment of recurrent respiratory tract infection in children and its effect on immune function.METHODS: 157 children aged between 3-10 with recurrent respiratory tract infection admitted into Beijing Children’s Hospital Affiliated to Capital Medical University from Jan. 2017 to Dec. 2018 were selected and divided into treatment group（ 79 cases） and control group（ 78 cases） via random number table. The control group was given conventional symptomatic treatment（ including anti-febrile

antitussive and catarrh relieve） and anti-infective therapy

while the treatment group was given compound Taizishen granule based on the control group. The clinical efficacy of both groups was observed

differences in immune globulin G（ Ig G）

immune globulin A（ Ig A） and immune globulin M（ Ig M）levels between two groups before and after treatment were compared. RESULTS: The total effective rate of treatment group was 91. 14%（ 72/79）

which was significantly higher than that of the control group（ 73. 08%

57/78）

with statistically significant difference（ P<0. 05）. At 1 month after treatment

the Ig G and Ig A levels of treatment group were significantly higher than those of before treatment and the control group

with statistically significant differences（ P <0. 05）; while there was no statistical significance in the difference of Ig M levels between two groups（ P > 0. 05）.CONCLUSIONS: The combination of compound Taizishen granule and conventional western medicine can reduce the recurrence rate of recurrent respiratory tract infection in children

which can significantly improve children’s immunity.