OBJECTIVE: To investigate the application of national essential drugs in stomatology hospital

so as to provide reference for the rational application of national essential drugs in clinic. To explore and optimize the management mode of national essential drugs in stomatology hospital

so as to provide reference for effectively reducing the burden of patients’ drug costs. METHODS: The application data of national essential drugs in HIS system of Hospital of Stomatology

Sichuan Universit（ hereinafter referred to as "our hospital "） in 2018 was investigated

statistical analysis was conducted according to drug categories and sales amount

and corresponding management measures based on the analysis results was formulated. RESULTS: In 2018

among 194 kinds of drugs in our hospital

74 categories were national essential drugs（ mainly for chemical drugs and biological products

totally 70 categories）

38. 14% of the total drugs in our hospital. The consumption sum of drugs in our hospital were 21. 230 7 million yuan

of which national essential drugs were 6. 638 5 million yuan（ accounted for 31. 27%）. The top 3 drugs ranked by consumption sum were respectively inhalation of sevoflurane

piperacillin tazobactam injection and cefuroxime injection

the proportion of consumption sum of the three drugs was 50. 11%. In order to innovate the national essential drugs management model

the essential drugs management team should be established to take measures such as informatization construction

quantitative assessment indicators

special prescription review and enhanced training.CONCLUSIONS: The application of national essential drugs in our hospital conforms to the characteristics of oral specialty drugs. It is necessary to explore the management mode of national essential drugs

promote the rational application of drugs

and effectively reduce the burden of patients.