OBJECTIVE: To probe into the effects of Shensong Yangxin capsules combined with metoprolol on serum cathepsin S（ Cat S）

hematocrit（ HCT） and pain improvement in elderly patients with unstable angina pectoris.METHODS: Totally 120 elderly patients with unstable angina pectoris admitted into the First Hospital of Wuhan from Jan. 2016 to Jan. 2018 were extracted to be divided into the observation group and the control group via the random number table

with 60 cases in each group. The control group was treated with metoprolol

while the observation group received Shensong Yangxin capsules combined with metoprolol

both groups were treated for 4 weeks. The clinical efficacy

Cat S

HCT

visual analogue scale（ VAS） and angina pectoris attack in two groups were observed.RESULTS: The total effective rate in the observation group was 90. 00%（ 54/60）

significantly higher than that in the control group 68. 33%（ 41/60）

with statistically significant difference（ P < 0. 05）. After treatment

the levels of Cat S and HCT in two groups were significantly lower than before treatment

and the observation group was significantly lower than the control group

the differences were statistically significant（ P < 0. 05）. The frequency and duration of angina pectoris attack in two groups were significantly improved compared with that before treatment

and the frequency of angina pectoris attack in the observation group was significantly lower than that in the control group

and the duration of angina pectoris was significantly shorter than that in the control group

with statistically significant differences（ P<0. 05）. After treatment

VAS scores in two groups were significantly lower than those before treatment

and the observation group was significantly lower than the control group

with statistically significant differences（ P <0. 05）. CONCLUSIONS: The efficacy of Shensong Yangxin capsules combined with metoprolol in the treatment of elderly patients with unstable angina pectoris is remarkable

which can significantly improve the levels of Cat S and HCT in patients

and has positive significance for the improvement of angina pectoris.