Objective: To probe into the clinical features

risk factors and prognosis of necrotizing enterocolitis (NEC) in preterm infants and term infants. Methods: Totally 325 neonates diagnosed with NEC in the Children’s Hospital of Chongqing Medical University from 2016 to 2018 were retrospectively analyzed with the clinical data

clinical manifestations and major complications

and all children were divided into the term infant group and preterm infant group according to the gestational age. Results: Blood stool and vomiting were the most common clinical manifestations of the term infants (P<0.05)

abdominal distension and hypoactive bowel sounds were the most common clinical manifestations of the preterm infants (P<0.05). The incidence of NEC complications in the preterm infant group was significantly higher than that in the term infant group (P<0.05). There was statistically significant difference between the term infant group and the the preterm infant group in poor prognosis (P<0.01). Neonatal sepsis

neonatal shock and congenital heart disease were independent risk factors affecting the clinical outcome of NEC (P<0.05). Conclusion: Paying attention to the prevention and treatment of high risk factors of all gestational age groups of neonates

closely observing clinical manifestations

auxiliary examination

prevention and reduction of complications are helpful to reduce the incidence of NEC and improve the prognosis.