Objective: To observe the effect and safety of remazolam in reducing the incidence of agitation after sevoflurane anesthesia in children

and to provide theoretical support for improving the quality of anesthesia in children. Methods: A total of 90 children who needed laparoscopic high ligation of hernia sac in the Department of Anesthesia and Perioperative Medicine of The 900th Hospital of Joint Logistics Support Force

PLA from March 2020 to March 2021 were randomly divided into group A and group B

with 45 cases in each group. Group A was given sevoflurane anesthesia

and group B was given combined anesthesia of remazolam and sevoflurane. The anesthetic effect (anesthesia induction time

respiratory recovery time

awakening time

extubation time)

changes of vital signs (mean arterial pressure

heart rate)

agitation during recovery such as pediatric anesthesia emergence delirium (PAED) score

Watcha score

incidence of agitation and adverse reactions were compared between the two groups. Results: The anesthesia induction time

respiratory recovery time and awakening time in group B were shorter than those in group A (P<0. 05). The mean arterial pressure and heart rate in group B were higher than those in group A (P<0. 05). The PAED score and Watcha score of group B were higher than those of group A

and the incidence of agitation was lower in group B than in group A (P<0. 05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P >0. 05). Conclusion: The application effect of remazolam in sevoflurane anesthesia in children is significant

which can improve the anesthetic effect

stabilize the vital signs of children

reduce the incidence of agitation after sevoflurane anesthesia in children

and does not increase adverse reactions. It has high effectiveness and safety

and is worthy of application.