Objective: To explore the role of clinical pharmacists in the treatment of intracranial Aspergillus infection in obese children. Methods: Clinical pharmacists participated in the drug therapy of intracranial Aspergillus infection in an obese child

recommended the initial dose of the obese child

monitored the blood concentration of voriconazole

detected metabolic genes and adjusted the dose

which reduced the incidence of adverse drug reactions related to voriconazole. Results: After 1 month of anti-infection treatment

the child was discharged from hospital with improved condition. Conclusion: For rare intracranial Aspergillus infection

clinical pharmacists should carry out individualized drug therapy for obese children to ensure the medication safety and effectiveness for children.