Objective: To improve the accuracy of split use of oral tablets in children and ensure the safety and effectiveness of the clinical medication. Methods: Based on the quality control circle activities

the existing problems were analyzed and possible improvement measures were proposed

the PDCA cycle practice was adopted to evaluate the improvement methods by comparing and analyzing the accuracy of split use of oral tablets in children before and after improvement

and standardized workbooks were formulated. Results: The main causes of errors in split use of oral tablets in children were low split dose and non-standard operation. After using powdered packaging and standardized operation training and assessment

the accuracy rate of split use of oral tablets increased from 80.0% to 95.0. Conclusion: The implementation of quality control circle activities can solve the problem of low accuracy of split dose. The accuracy of split use of oral tablets in children can be improved by powdered packaging and standardized operation training and assessment

so as to guarantee the safety and effectiveness of the clinical medication.