Objective: To evaluate the effect of pharmaceutical care provided by clinical pharmacists in otolaryngology department

and to explore the role of clinical pharmacists in promoting the rational use of antibiotics in clinic. Methods: The role of clinical pharmacists in providing pharmaceutical care in clinical practice was evaluated from two aspects. The first was to retrospectively analyze the irrational use of antibiotics in the otolaryngology department of our hospital during perioperative period

and to formulate and implement intervention measures. The second was to analyze the reasons for high daily defined dose system (DDDs) in this ward

and to formulate and implement intervention measures to lower the DDDs of antibiotics. Results: After clinical pharmacists carried out pharmaceutical care in otolaryngology department of our hospital

the irrational use rate of antibiotics during perioperative period decreased from 91.92% to 40.44%

manifested in improper medication indication

improper drug varieties

improper medication timing

and improper medication duration. The mean use intensity of antibiotics decreased from 20.57 to 13.40 after 6 months of intervention. Conclusion: After implementation of pharmaceutical care provided by clinical pharmacists in otolaryngology department

the irrational use of antibiotics during perioperative period has been significantly improved

and the use intensity of antibiotics has been decreased significantly. However

the irrational use of antibiotics still exists

which requires further joint efforts of clinical pharmacists and clinicians.