Wang Juping, Li Zhiling, Liu Hongxia, et al. A Case Report of Liver Failure in a Child Induced by Ibuprofen[J]. 2022,28(11):28-31. DOI: 10.13407/j.cnki.jpp.1672-108X.2022.11.008.
Objective: To analyze the drug treatment methods of liver failure in a child induced by ibuprofen
so as to explore the role of clinical pharmacists in drug treatment monitoring. Methods: The clinical data of a child with acute liver failure induced by ibuprofen were analyzed
and the treatment regimen was discussed in combination with relevant literature. Results: According to the conditions of liver failure
plasma exchange detoxification
compound glycyrrhizin
polyene phosphatidyl choline
ceftazidime and albumin were used
and the symptoms of the child were significantly improved. Conclusion: Liver injury induced by ibuprofen is generally mild and reversible
yet if it is found to induce severe liver injury
the liver injury should be treated promptly. Due to therapeutic drugs also have the potential to induce further liver injury
liver function indicators should be closely tested and therapeutic drugs should be selected rationally