A case of premature infant with gestational age of 34+2 weeks was given parenteral nutrition and octreotide acetate injection for the treatment of premature infant

low birth weight infant

pleural effusion and chylothorax. After the main therapeutic drugs such as intravenous nutrition and octreotide injection were discontinued

that is

41 d after hospitalization

the liver function test showed significant abnormalities

and the supplementary diagnosis of cholestatic hepatitis was made. After excluding possible causes such as genetic metabolism

it was judged to be drug-related cholestasis

which was highly suspected to be induced by the prolonged application of parenteral nutrition. After diagnosis

compound glycyrrhizin tablets and ursodeoxycholic acid capsules were given to improve the liver function

and regular follow-up was performed after discharge. After 45 d of liver protection treatment

the liver function was normal

and the drug was discontinued.