Objective: To improve the clinical understanding of biliary pseudolithiasis complicated with liver function injury induced by ceftriaxone

and avoid the excessive treatment. Methods: A case of biliary pseudolithiasis complicated with liver function injury induced by ceftriaxone in Shanghai Children’s Hospital was analyzed and related literature were reviewed. Results: A child was hospitalized with right upper abdominal pain after continuous administration of ceftriaxone for 5 d. Abdominal ultrasound scan showed cholecystolithiasis and blood examination showed increased liver enzymes. After treatment with hepatoprotective drugs

the liver enzymes decreased significantly

and the child no longer complained with abdominal pain and other uncomfortable symptoms. After 38 d of treatment

the abdominal ultrasound scan showed that the gallstone disappeared

and the liver enzymes returned to the normal state. Conclusion: The incidence of biliary pseudolithiasis induced by ceftriaxone in children is relatively high

and there are a lot of influencing factors. Most children are asymptomatic

because gallstone generally disappear spontaneously

and no special treatment is required if there are no severe complications