Objective: To probe into the application status of drug manipulation for pediatric oral dosing in our hospital

so as to provide reference for ensuring the rational and safe medication of children. Methods: Medical orders of drug manipulation for pediatric oral dosing were extracted from Jun. 2018 to May 2019 in our hospital

and the drug information of manipulation for pediatric oral dosing was statistically analyzed

including age

gender

drug name

specification and manipulation dose. Results: A total of 1

080 children were enrolled

with 15

724 medical orders

among which the medical orders of urinary system with drug manipulation for pediatric oral dosing accounted for the largest proportion (4

282 entries

27.23%)

followed by drugs affecting allergy and immune function (2

202 entries

14.00%)

digestive drugs (2

149 entries

13.67%) and anti-infective drugs (1

403 entries

8.92%). Tablets accounted for the largest number of drug manipulation for pediatric oral dosing (10

434 entries

66.36%)

followed by hard capsules (1

329 entries

8.45%) and oral solutions (739 entries

4.70%). Conclusion: The existing specifications of our hospital cannot meet the clinical needs

and the prevalent phenomenon of drug manipulation for pediatric oral dosing poses a great danger to the medication safety

which requires the collaboration of the state

enterprises and hospitals to ensure the rational and safe medication for children.