Objective: To investigate the current status of cross-borde shopping of children’s drugs in China

and to analyze the problems in the application of children’s drugs from cross-borde shopping. Methods: Electronic questionnaire was used to collect the status and application of children’s drugs from cross-borde shopping in China

and to analyze parents’ awareness and the risk of parents’ application behavior of children’s drugs from cross-borde shopping. Results: The total number of participants in the survey was 6

202 cases

and 1

057 cases (17.04%) had the experience with cross-borde shopping of children’s drugs. The survey data showed that the age of children

education level of guardians and occupation of guardians significantly affected the behavior of guardians in cross-borde shopping of children’s drugs. Children aged from 1 to 3 years (22.33%) and from 4 to 7 years (21.11%) had higher proportion of behavior of guardians in cross-borde shopping of children’s drugs. The educational level of guardians significantly affected the cross-borde shopping of children’s drugs

with the highest proportion of cross-borde shopping for people with the master’s degree or above (22.08%). Among the guardians

civil servants and public institution staff were the profession with the highest proportion of cross-borde shopping (23.06%). Among those with cross-borde shopping experience

21.1% of guardians could fully understand the drug instructions

60.36% could only understand part of the drug instructions

9.84% could not understand the drug instructions completely

and 8.7% did not read the drug instructions. Conclusion: There is a great deal of blindness in the cross-borde shopping of children’s drugs

and most of the cross-borde shopping drugs are self-prepared drugs. The lack of professional guidance on indications and precautions for children’s drug application in guardians may lead to higher risks of drug application