Objective: To probe into the effects of compound lidocaine cream on lumbar puncture in children with tumor. Methods: A total of 292 children with leukemia and lymphoma received intrathecal injection of lumbar puncture from 2014 to 2016 in our hospital were extracted to be divided into the experimental group and the control group via the random number table

with 146 cases in each group. In the experimental group

with the lumbar puncture point as the center

the local skin with the radius of 5 cm was smeared with 0.5 mm compound lidocaine cream

covered with the medical 3M film for 2 h

and the film and cream were removed and routinely disinfected before lumbar puncture. The control group received lumbar puncture after local anesthesia with lidocaine injection. Improved facial expression scoring (FLACC) scale and Wong-Baker facial expression scale were used to evaluate the pain degree of the children

and the heart rate

respiration

blood pressure

success rate of puncture

discomfort and family satisfaction were recorded before and after puncture. Results: The degree of pain and discomfort after puncture in the experimental group were lower than those in the control group (P<0.05). After puncture

the heart rate

respiration and systolic blood pressure in the control group were significantly faster than those before puncture (P<0.05)

and the difference in heart rate

respiration and systolic blood pressure after puncture in the experimental group was not statistically significant (P>0.05). There was no significant difference in success rate of puncture between two groups

yet the satisfaction of the family members in the experimental group was significantly higher than that of the control group. Conclusion: Compound lidocaine cream can significantly reduce the pain caused by repeated puncture in the treatment of children with tumor

improve the quality of life of children and the efficiency of clinicians

and is worthy of clinical application.