Objective: To explore the clinical manifestations

early diagnosis

treatment options and prognosis of patients with Kawasaki disease shock syndrome (KDSS). Methods: The clinical data of 17 patients with KDSS were retrospectively collected. Four patients hospitalized at the same time were selected as the control group for each KDSS patient. The clinical characteristics and laboratory characteristics were compared. Results: Heart damage in the KDSS group was more serious. Compared with the control group

the left ventricular ejection fraction in the KDSS group decreased

and the amino terminal brain natriuretic peptide increased

which could be used as an effective indicator for early identification of KDSS. The incidence of coronary artery damage in the KDSS group was significantly higher than that in the control group. The platelet count in the KDSS group decreased; the number of neutrophils and C-reactive protein in the KDSS group were significantly higher than those in the control group. Conclusion: KDSS is a kind of severe form of Kawasaki disease

and its systemic inflammation and cardiac injury are more severe than those of non shock Kawasaki disease. The treatment of gamma globulin and vasoactive drugs is safe and effective

and follow-up of most patients shows good prognosis.