Wu Lunhui, Wei Yonggang, Liu Puxian, et al. Comparison of Efficacy of Budesonide and Salbutamol Aerosol Inhalation at Different Temperatures in Adjuvant Treatment of Children with Bronchiolitis[J]. 2021,27(2):18-21.
Wu Lunhui, Wei Yonggang, Liu Puxian, et al. Comparison of Efficacy of Budesonide and Salbutamol Aerosol Inhalation at Different Temperatures in Adjuvant Treatment of Children with Bronchiolitis[J]. 2021,27(2):18-21. DOI: 10.13407/j.cnki.jpp.1672-108X.2021.02.006.
Objective: To compare the clinical efficacy of budesonide and salbutamol aerosol inhalation at different temperatures in adjuvant treatment of children with bronchiolitis. Methods: Totally 100 children with bronchiolitis admitted into our hospital from Jun. to Dec. 2018 were extracted to be randomly divided into the control group and the observation group
with 50 cases in each group. Both groups were treated with aerosol inhalation on the basis of conventional treatment. The control group was treated with budesonide and salbutamol aerosol inhalation at the conventional temperature of 22 to 24 ℃
and the observation group received budesonide and salbutamol aerosol inhalation at temperature of 35 to 37 ℃. Disappearance time of clinical symptoms and length of stay were observed. Lung function indexes
serum procalcitonin (PCT) and C-reactive protein (CRP) levels of two groups were compared before and after treatment . The treatment effects and incidence of adverse drug reactions of two groups were compared. Results: The disappearance time of clinical symptoms and the length of stay in the observation group were shorter than those in the control group. After 5 d of treatment
the pulmonary function indexes were better than those in the control group
and the levels of serum PCT and CRP were lower than those in the control group (P<0.05). The total effective rate of the observation group was higher than that of the control group after 5 d of treatment (P<0.05)
there were no obvious adverse drug reactions in two groups. Conclusion: Compared with the conventional temperature of 22 to 24 ℃
the adjunctive treatment budesonide and salbutamol aerosol inhalation at temperature of 35 to 37 ℃ for children with bronchiolitis is more effective
which can quickly relieve the clinical symptoms and signs