Objective: To probe into the role of clinical pharmacists in anti-infective treatment of neonatal Burkholderia cepacia infection. Methods: Retrospective analysis was performed on clinical pharmacists’ participation of levofloxacin in the treatment of neonatal Burkholderia cepacia infection. Results: Clinical pharmacists assessed the risks and benefits of levofloxacin for neonatal infection

and participated into the adjustment of anti-infective regimens. After comprehensive treatment

the child’s respiration was better than before

and the body temperature returned to the normal state. Conclusion: After fully assessing the risks and benefits

fluoroquinolones can be used to treat life-threatening or difficult-to-treat children with infections

which will help to reduce the mortality of pediatrics with severe Burkholderia cepacia infection.