Objective: To observe the clinical effects of alveolar lavage combined with inhalation alveolar lavage with acetylcysteine solution in the treatment of atelectasis in children. Methods: Sixty children with atelectasis admitted into our hospital from Jan. 2018 to Nov. 2019 were extracted to be randomly divided into the control group and the observation group

with 30 cases in each group. The control group was given bronchoscopic alveolar lavage

while the observation group received bronchoscopic alveolar lavage combined with inhalation alveolar lavage with acetylcysteine solution. The clinical efficacy

disappearance time of lung rales

recovery time of body temperature

length of stay

times of alveolar lavage and imaging recovery time

arterial blood gas indexes including arterial partial pressure of blood carbon dioxide (PaCO2)

partial pressure of blood oxygen (PaO2) and blood oxygen saturation (SaO2)

and adverse drug reactions of two groups were compared. Results: The total effective rate in the observation group was significantly higher than that in the control group

with statistically significant difference (P<0.05). After treatment

the disappearance time of lung rales

recovery time of body temperature

length of stay

times of alveolar lavage and imaging recovery time in the observation group were significantly shorter than those in the control group (P<0.05). PaCO2 decreased (P<0.05)

and PaO2 and SaO2 increased (P<0.05) in both groups of children

and the observation group was better than the control group (P<0.05). There were no statistically significant difference in the adverse drug reactions between two groups (P>0.05). Conclusion: The efficacy of bronchoscopic alveolar lavage combined with acetylcysteine solution alveolar lavage in the treatment of atelectasis in children is significant

which can effectively improve the clinical symptoms of children and shorten the course of disease without increasing adverse drug reactions