Objective: To analyze the clinical characteristics

pathogenic bacteria and drug resistance of children with bacterial diarrhea

so as to guide clinical diagnosis and treatment. Methods: Retrospective analysis was conducted on clinical data of 296 children with bacterial diarrhea admitted into our hospital from Jan. to Dec. 2017. Results: Among the 296 children

171 cases were male and 125 cases were female

the ratio of male to female was 1.37∶1. There were 239 children under 5 years old

accounting for 80.74%. The onset time was concentrated in 5 to 9 months (79.39%). The clinical manifestations were diarrhea

fever

abdominal pain

mucous stool

some of which were bloody stool

and the number of stools was 5 to 10 times. There were 166 cases (56.08%) of Salmonella

73 cases (24.66%) of Escherichia coli

41 cases (13.85%) of Orthomonas shigella

15 cases (5.07%) of Vibrio parahaernolyticus

and 1 case (0.34%) of Shigella. All bacteria were sensitive to imipenem and piperacillin tazobactam (with sensitivity rate of 100%). The sensitivity rates of Salmonella and diarrhogenic E. coli to ceftazidime and cefatriaxone were 75.00%

93.55% and 67.31%

80.65%

respectively

with different degrees of resistance to the three generation cephalosporins. V. parahaemolyticus was highly sensitive to drugs. Conclusion: Children with bacterial diarrhea have higher incidence

faster transmission and higher drug resistance. Clinical examination should be completed as soon as possible

and antibiotics should be chosen rationally.