Objective: To probe into the effects of congenital lung cystic lesions on children’s lung function

so as to provide reference for clinical surgical treatment. Methods: From Jan. 2014 to Sept. 2018

totally 49 children diagnosed with congenital lung cystic lesions in Children’s Hospital of Chongqing Medical University were extracted

preoperative lung function was measured and statistically analyzed. Among them

23 children were <42 months

and the lung function was measured by tidal breathing method; 26 children were ≥42 months

and the lung function was measured by conventional ventilation method. Results: There were 18 cases (36.8%) of bronchogenic cysts (BC)

among which 5 cases (<42 months) had abnormalities in TPTEF/TE

VPEF/VE

PF/V25 and TI/TE

indicating moderate obstruction of small airway and mild obstruction of large airway; and 7 cases (≥42 months) had abnormalities in FVC

FEV1

FEF75 and MMEF

suggesting mild mixed ventilation dysfunction. There were 15 cases (30.6)% of congenital cystic adenomatoid malformation (CCAM)

among which 8 cases (<42 months) had abnormalities in TPTEF/TE

PF/V25 and TI/TE

suggesting mild obstruction of large and small airway; 7 cases (≥42 months) had normal lung function. There were 10 cases (20.4%) of pulmonary sequestration (PS)

among which 7 cases (<42 months) had abnormalities in TEF50/TIF50 and TI/TE

suggesting mild obstruction of large airway; 3 cases (≥42 months) had normal lung function. There were 6 cases (12.2%) of congenital lobar emphysema (CLE)

among which 3 cases (<42 months) had abnormalities in TPTEF/TE

VPEF/VE

PF/V25

TEF50/TIF50 and TI/TE

suggesting moderate obstruction of small airway and mild obstruction of large airway; 3 cases (≥42 months) had normal lung function. In terms of clinical manifestations

11 cases (47.8%) in the <42-month group had the history of lung infection

and 20 cases (76.9%) in the ≥42-month group had the history of lung infection. Conclusion: Congenital lung cystic lesions causes lung function impairment in children

mainly manifested by airway dysfunction at different degree. The degree of impairment of lung function is more obvious in younger age groups

and older age groups are more prone to have repeated lung infections. Early surgery is the preferred treatment option.