Objective: To investigate the characteristics and clinical significance of hemoglobin (Hb) and vitamin D (1

25(OH)2D3) levels in children with severe caries. Methods: From Jan. 2017 to Feb. 2018

a total of 106 children with dental caries were extracted

including 44 cases of severe caries (severe group) and 62 cases of non severe caries (non severe group)

and 60 cases of caries free children were selected as the control group. The levels of Hb and 1

25 (OH) 2D3 in each group were detected. Results: The levels of Hb and 1

25 (OH) 2D3 in the severe group were respectively (108.81±6.72) g/L and (64.15±9.87) nmol/L

significantly lower than those in the non severe group and the control group (P<0.05). The levels of Hb and 1

25 (OH) 2D3 in the non severe group were respectively (113.03±7.20) g/L and (72.06±10.64) nmol/L

significantly lower than those in the control group (P<0.05). The number of decayed-missing-filled tooth (dmft) in the severe group was 8.90±1.11

significantly higher than that in the non severe group (P<0.05). The levels of Hb and 1

25 (OH) 2D3 in the severe group were negatively correlated with dmft (r=-0.482 and -0.454

P<0.05). The levels of Hb and 1

25 (OH) 2D3 in the non severe group were not correlated with dmft (P>0.05). Conclusion: The levels of Hb and 1

25(OH)2D3 in children with severe caries are significantly lower

and there is a certain correlation with dmft in children

which deserves further study.