Zhang Juan, Tian Wei, Dai Baochun, et al. Serum Vitamin D Levels in Children with Mycoplasma Pneumoniae Pneumonia and Its effects on Immune Function[J]. 2020,26(1):4-6.
Zhang Juan, Tian Wei, Dai Baochun, et al. Serum Vitamin D Levels in Children with Mycoplasma Pneumoniae Pneumonia and Its effects on Immune Function[J]. 2020,26(1):4-6. DOI: 10.13407/j.cnki.jpp.1672-108X.2020.01.002.
Objective: To probe into the changes of serum vitamin D (VitD) levels in children with Mycoplasma pneumoniae pneumonia (MPP) and its effects on immune function. Methods: A total of 100 MPP children diagnosed in pediatrics in our hospital from Jan. 2016 to Jan. 2017 were selected as the MPP group
and 100 healthy children were selected as the control group. Serum levels of 25-(OH)D3
IgM
IgA
IgG
complement C3
complement C4 and T lymphocyte subsets were detected in two groups. The MPP group was divided into the mild group and the severe group according to the severity of the disease. Results: The levels of 25-(OH)D3
IgM
IgA
IgG
complement C3
complement C4
CD3+
CD4+
CD4+/CD8+ in the MPP group were lower than those in the control group (P<0.01)
and there was no significant difference in levels of CD8+ between two groups (P>0.05). Serum levels of 25-(OH)D3
IgM
IgA
IgG
complement C3
complement C4
CD3+
CD4+
CD4+/CD8+ in the severe group were lower than those in the mild group
and the levels of CD8+ were higher than those in the mild group (P<0.01). Conclusion: The serum levels of 25-(OH)D3 and indicators of immune function are decreased in MPP children. The monitoring on serum levels of 25-(OH)D3 and immune function can provide guidance for clinical treatment.
关键词
肺炎支原体肺炎维生素D免疫功能
Keywords
Mycoplasma pneumoniae pneumoniatamin Dmmune function