Objective:To investigate the prognosis factors

therapy and clinical manifestations of primary gastric non-Hodgkin lymphoma.Methods:The clinical and pathological data of 51 patients with primary gastric non-Hodgkin lymphoma were reviewed.The clinical data were analyzed by log-rank

COX and Kaplan-Meier method.Results:Histopathological types of 51 patients were classified into 23(45.1%) of mucosa-associated lymphoid tissue lymphoma

17(33.3%) of diffuse large B cell lymphoma

1(2.0%) of lymphoplasmacytic lymphoma

3(5.9%) of T cell type and 7(13.7%)of non-specific type

respectively.Thirty-four(66.7%) patients were in stage Ⅰand Ⅱ

and seventeen(33.3%) in stage Ⅲ and Ⅳ.The overall survival rates at 5 years was 47.1%.Univariate analysis showed that patients with LDH≥240 U/L(P=0.001)

clinical stage≥Ⅲ(P=0.002) and IPI score≥3(P=0.002) had poorer prognosis.Mucosa-associated lymphoid tissue lymphoma had richer than others.Multivariate analysis showed LDH was independent prognostic factor.Conclusion:The majority of primary gastric lymphoma is mucosa-associated lymphoid tissue lymphoma

and the prognosis is richer than others.Patients with LDH ≥240 U/L means the prognosis is poorer than other patients.Chemotherapy-dominated modality is recommended for patients with PGNHL.