Objective:To approach clinical curative effects of combined therapy including operation

radiotherapy

chemotherapy

and immunobiologic therapy for synovial sarcoma.Methods:79 cases of synovial sarcoma with the combined therapy from 2000 to 2010 were randomly selected to evaluate the clinical curative effects and their prognosis.Results:The mean follow-up time was 6 years(3~10 years).Combined therapies included operation

radiotherapy

chemotherapy

and immunobiologic therapy.The rates of regional recurrence and metabasis were as follows:28.3% and 41.7% respectively in limbs group(60 cases);0% and 10.5% respectively in trunk group(19 cases).The rates of regional recurrence and metabasis of limbs group were higher than those of trunk group.The rate of survival without tumor for 3 years was 78.5%;the rate of general effective survival was 89.9%;those for 5 years were 65.8% and 75.9% respectively.Conclusion:The time of diagnosis and treatment and the location of the sarcoma are very important to their prognosis.To make a correct diagnosis and to give a wide and thorough removal in the cleaning of regional lymphadenectasis in early stage and the combined therapies including radiotherapy

chemotherapy

and immunobiologic therapy pre-and post-operation is the key to the improvement of the clinical curative effect.