LIU Zu-li, et al. Effect of intensities of electroacupuncture on C-reactive protein and interleukin-6 in adipose tissues from high fat diet-induced obese rats[J]. Journal of Chongqing Medical University, 2011,36(4):429-432.
LIU Zu-li, et al. Effect of intensities of electroacupuncture on C-reactive protein and interleukin-6 in adipose tissues from high fat diet-induced obese rats[J]. Journal of Chongqing Medical University, 2011,36(4):429-432. DOI: 10.13406/j.cnki.cyxb.2011.04.004.
Objective:To investigate the effect of intensities of electroacupuncture on C-reactive protein(CRP)and interleukin-6(IL-6) in adipose from high fat diet-induced simply obese rats.Methods:Male SD rats were randomly divided into control group(CG
n=10)
model group with high fat diet only(MG
n=10)
electroacupuncture groups with high fat diet fed rats stimulated by either 2 V(2 V EA
n=10)or 1v of electroacupuncture(1 V EA
n=10).Electroacupuncture(10 Hz
2 V EA:2 V
1 V EA:1 V)was applied to acupuncture points"Zu san li" and "San yin jiao"for 15min everyday and for 14 days.Lee’s index in each group were detected.The contents of CRP in epididymis adipose tissue were detected by ELISA.The expression of IL-6 in epididymis adipose tissue was detected by Western blotting.Results:Lee’s index and expression of CRP
IL-6 from two EA groups were significantly decreased compared with the model group(P<0.01)
and obvious change was observed between the two EA groups(P<0.01
P<0.05).Conclusion:Electroacupuncture can reduce obese rats’weight
decrease the expressions of CRP and IL-6 in epididymis adipose tissue and improve inflammatory state in obese rats.Moreover
2 V EA group exhibits a better effect compared with 1 V EA group.