LOU Dan-dan, et al. Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder[J]. Journal of Chongqing Medical University, 2011,36(3):342-343.
LOU Dan-dan, et al. Effect of medified electroconvulsive therapy on the cognition of patients with major depression disorder[J]. Journal of Chongqing Medical University, 2011,36(3):342-343. DOI: 10.13406/j.cnki.cyxb.2011.03.028.
Objective: To estimate the influence of modified electroconvulsive therapy(MECT) on the cognition of patients with major depression.Methods: Patients metting CCMD-3 criteria for major depression
whose scores of HAMD 17-item were above 24
were treated with bilateral
brief pulse
square-wave stimulus
dose titration MECT.Before and after the 1st and 6~8th course of treatment
Hamilton depression scale and Wechsler memory scale were tested.Results:There was significant amelioration of clinical symptoms after MECT(P <0.01)
but it had negative impact on memory
which would last till the 6~8th course of treatment.Conclusion: MECT may improve the symptoms of patients with severe depression and irreversibly influnce the memory.