YI Xue-lan. Observation of the ovarian function for surgical ovarian reservations in patients with early cervical cancer[J]. Journal of Chongqing Medical University, 2011,36(1):98-100.
YI Xue-lan. Observation of the ovarian function for surgical ovarian reservations in patients with early cervical cancer[J]. Journal of Chongqing Medical University, 2011,36(1):98-100. DOI: 10.13406/j.cnki.cyxb.2011.01.033.
Objective:To observe the ovarian function for surgical ovarian reservations in patients with early cervical cancer
and analyze related factors.Methods:We conducted a at least six months followed up for 98 patients with early cervical cancer who accepted radical hysterectomy with ovaries reserved.Sex hormones were detected by chemiluminescence immunoassay.Ovarian failure was confirmed by FSH> 40 IU / L
E2 <50 pmol/L.Results:A total of 17 patients(17.3%) were confirmed of ovarian failure in the 6th month after surgery.The morbidity of ovarian failure in 12th month
24th month
36th month was 24.7%
25.3%
24.5%
respectively.It was affected by age and postoperative radiotherapy.After multi factors adjusted
the OR of ovarian failure for > 40 years and <40 years was 3.589;ant the OR was 4.354 for patients with postoperative radiotherapy and without postoperative radiotherapy.Conclusion:There is some ovarian failure morbidity in young patients with early cervical cancer after retain ovarian surgery
which was affected by age and postoperative radiotherapy.