SONG An-lin, et al. Neuropathological study of frontal lobe of schizophrenia patients[J]. Journal of Chongqing Medical University, 2010,35(12):1924-1927.
SONG An-lin, et al. Neuropathological study of frontal lobe of schizophrenia patients[J]. Journal of Chongqing Medical University, 2010,35(12):1924-1927. DOI: 10.13406/j.cnki.cyxb.2010.12.020.
Objective:To study pathological changes and the etiology existing in frontal lobes of schizophrenia group.Methods:Frontal lobes of schizophrenia and normal control group were harvested and made into paraffin sections
and microscopic and stereological methods were used to study pathological changes existing in frontal lobes.Results:In schizophrenic group
a large number of pyramidal cells condensed;nerve cells degenerated and necrosed;glial cells proliferated;a large number of amyloid corpuscles formed
and satellitosis and neuronophagia significantly increased compared with the control group.Conclusion:The pathological changes in frontal lobe may be closely related with schizophrenia.