Objective:To investigate the effects of Hemorrheological factors and related trace elements on oral recurrent aphthae ulcer (RAU). Methods:Selected 83 patients with RAU from volunteer blood donors. Detected the Hemorrheological indicators and the contents of Mg

Fe

Zn

Se and Cu. Comparative Analysised them with healthy volunteers. Results : The patients with RAU’s levels of whole blood viscosity

whole blood reduced viscosity

plasma viscosity and hematocrit are higher than the control one ( P<0.05 ) .Erythrocyte electrophoresis time is prolonged

and erythrocyte sedimentation rate is dropped ( P<0.05 ) .The contents of Zn and Se are lower than the control one ( P<0.05 ) . However

there is no statistical significance about the contents of Mg

Fe and Cu between the two groups ( P>0.05 ) . Conclusion : Patients with RAU may be lack of Zn and Se.Furthermore

there are changes of Hemorrheological circumstances.This research provide references for the clinical treatments of RAU by means of improving blood circulation or supplement Zn and Se rationally.