Objective:To analyze the clinical treatment of childhood severe community-acquired pneumonia

in order to provide theoretical evidence for improving the cure rate and decreasing mortality rate. Methods:272 children with severe community-acquired pneumonia were admitted in Chongqing Children’s Hospital from December 2008 to November 2009.Their clinical data

especially the condition of treatment and prognosis

were collected and statistically analyzed.Results:(1)In 272 children

194 were cured and 54 improved their condition

with treatment efficiency being 91.2%;17 quitted the treatment and 7 died

with treatment inefficiency being 8.8%

and mortality being 2.57%

accounting for 11.5 times as much as the overall mortality of pneumonia in children in the same period. (2)The efficiency of empirical therapy group was significantly higher than another group which were changed to specific treatment after ineffective empirical treatment

and the difference was statistically significant. There were statistical significant differences between groups of hormone therapy and non-hormone therapy

mechanical ventilation and non-mechanical ventilation

vasoactive drugs therapy and non-vascular active drug treatment. The efficiency of supportive treatment was better than that of non-supportive treatment group

but the difference was not statistically significant. Conclusion:Comprehensive treatment should be emphasized in childhood severe pneumonia. Reasonable selection of initial antibiotics is critical for improving the prognosis of severe pneumonia. Clinicians should pay attention to the clinical conditions of patients

epidemiological features of local pathogens and antibiotic susceptibility test when choosing the initial empirical drug. Based on the effective antibiotic therapy

a reasonable

short-term use of small doses of hormones can improve the prognosis. Vasoactive drug and supportive therapy can improve the curative effect. Mechanical ventilation should be used timely if children develop serious breathing disorders.