Objective:Tostudythe earlywarningmeaningofprethrombotic state test before thrombosis caused byPICC. Methods:Clinical data of 30 patients selected randomly in our department during 2009.6.19~2010.2.22 was analyzed retrospectively. All the parameters brought into our study included PT

APTT

TT

PLT

Fbg

FDP and D-dimer. Every parameter was dynamically detected 3 times

0~1 days before (T0)

2~3 days after (T1)

4~11 days after (T2) PICC inserted. Three values of each parameter were compared in pairwise comparison. Results:The difference of PLT between T0 and T1 was significant (P<0.05). There was no significant difference in PT

APTT

TT

Fbg

FDP and D-dimer between T1 and T0 (P>0.05). Between T0 and T2

T1 and T2

there was no significant difference in all the 7 parameters(P>0.05). Conclusion:As the significant difference in PLT between T0 and T1

PLT test before and 2~3 days after PICC inserted may have great meaning of early warning thrombosis.