Objective:To compare the velocity and accuracy of constant speed infusion flow regulator and common round clip-general infusion flow regulator to improve drug safety of intravenous chemotherapy in children with solid tumors. Methods:From April 2009 to January 2010

198 patients with pediatric solid tumors were transfused with constant speed regulator control flow in single day and common round clip-general infusion flow regulator control in double day. Puncture site was in the back of the hand venous network in children. The input speed per hour was adjusted according to doctor’s advice about the functioning

dosage

and timing. The infusion time and the local complications were observed. Results:The drug concentrations and vascular status were not significantly different in two kinds of infusion methods (P>0.05). However

constant speed regulator controled flow no matter the change of position and activity of the patients and liquid scale in bottle.Conclusion:Constant speed infusion flow regulator has many advantages including accuracy scale flow

velocity stability and flow rate constant. It increases the intravenous chemotherapy drug safety and effectiveness in children with pediatric solid tumors.